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Background The emergence of Anopheles populations capable of withstanding lethal doses of insecticides has weakened the efficacy of most insecticide based strategies of vector control and, has highlighted the need for further studies on the mechanisms of insecticide resistance and the various fa...


Djouaka, R.F.Bakare, A.A.Bankole, H.S.Doannio, J.M.C.Coulibaly, O.N.Kossou, H.Tamo, M.Basene, H.I.Popoola, K..K.Akogbeto, M.C.[Does the spillage of petroleum products in Anopheles breeding sites have an impact on the pyrethroid resistance?]Does the spillage of petroleum products in Anopheles breeding sites have an impact on the pyrethroid resistance?

Background Although vector control strategies, such as insecticide-treated bed nets (ITNs) and indoor residual spraying (IRS) have been effective in Kenya the transmission of malaria continues to afflict western Kenya. This residual transmission is driven in part by Anopheles arabiensis, known fo...


Lozano-Fuentes, SaulKading, R.C.Hartman, D.A.Okoth, Edward A.Githaka, Naftaly W.Nene, VishvanathPoche, R.M.[Evaluation of a topical formulation of eprinomectin against Anopheles arabiensis when administered to Zebu cattle (Bos indicus) under field conditions]Evaluation of a topical formulation of eprinomectin against Anopheles arabiensis when administered to Zebu cattle (Bos indicus) under field conditions

Background: Knowledge on the spread and distribution of insecticide resistance in major malaria vectors such as Anopheles funestus is key to implement successful resistance management strategies across Africa. Here, by assessing the susceptibility status of an inland population of An. funestus Gi...


Djouaka, R.Riveron, J.M.Yessoufou, A.Tchigossou, G.Akoton, R.Irving, H.Djegbe, I.Moutairou, K.Adeoti, R.Tamò, M.Manyong, Victor M.[Multiple insecticide resistance in an infected population of the malaria vector Anopheles funestus in Benin]Multiple insecticide resistance in an infected population of the malaria vector Anopheles funestus in Benin

The development of cerebral malaria (CM) in mice with Plasmodium berghei ANKA infection is under genetic control. Brain gene-expression patterns were investigated in well-defined genetically CM-resistant (CM-R; BALB/c and DBA/2) and CM-susceptible (CM-S; C57BL/6 and CBA/J) mice by use of cDNA mic...


Delhaye, N.F.Coltel, N.Puthier, D.Flori, L.Houlgatte, R.Iraqi, F.A.Nguyen, C.Grau, G.E.Rihet, P.[Gene-expression profiling discriminates between cerebral malaria (CM) - susceptible mice and CM-resistant mice]Gene-expression profiling discriminates between cerebral malaria (CM) - susceptible mice and CM-resistant mice

Background: Insecticides resistance in Anopheles mosquitoes limits Long-Lasting Insecticidal Nets (LLIN) used for malaria control in Africa, especially Benin. This study aimed to evaluate the bio-efficacy of current LLINs in an area where An. funestus s.l. and An. gambiae have developed multi-res...


Akoton, R.Tchigossou, G.Djegbe, I.Yessoufou, A.Atoyebi, S.M.Tossou, E.Zeukeng, F.Boko, P.Irving, H.Adeoti, R.Riveron, J.Wondji, C.S.Moutairou, K.Djouaka, R.[Experimental huts trial of the efficacy of pyrethroids/piperonyl butoxide (PBO) net treatments for controlling multi-resistant populations of Anopheles funestus s.s. in Kpomè, Southern Benin]Experimental huts trial of the efficacy of pyrethroids/piperonyl butoxide (PBO) net treatments for controlling multi-resistant populations of Anopheles funestus s.s. in Kpomè, Southern Benin

Avian malaria parasites are prevalent around the world and infect a wide diversity of bird species. Here, we report the sequencing and analysis of high-quality draft genome sequences for two avian malaria species, Plasmodium relictum and Plasmodium gallinaceum. We identify 50 genes that are speci...


Böhme, U.Otto, T.D.Cotton, J.A.Steinbiss, S.Sanders, M.Oyola, Samuel O.Nicot, A.Gandon, S.Patra, K.P.Herd, C.Bushell, E.Modrzynska, K.K.Billker, O.Vinetz, J.M.Rivero, A.Newbold, C.J.Berriman, M.[Complete avian malaria parasite genomes reveal features associated with lineage-specific evolution in birds and mammals]Complete avian malaria parasite genomes reveal features associated with lineage-specific evolution in birds and mammals

A number of linkage studies in human populations have identified a locus ( pfbi) on Chromosome 5q31-q33 controlling Plasmodiun falciparum blood infection levels. This region contains numerous candidate genes encoding immunological molecules such as cytokines, growth factors and growth-factor rec...


Hernández Valladares, M.Rihet, P.Ole-MoiYoi, O.K.Iraqi, F.A.[Mapping of a new quantitative trait locus for resistance to malaria in mice by a comparative mapping approach with human chromosome 5q31-q33]Mapping of a new quantitative trait locus for resistance to malaria in mice by a comparative mapping approach with human chromosome 5q31-q33

Promising environmental mechanisms to control malaria are presently underutilized. Water level fluctuations to interrupt larval development have recently been studied and proposed as a low-impact malaria intervention in Ethiopia. One impediment to implementing such new environmental policies is t...


Reis, J.Culver, T.B.Block, Paul J.[Evaluating the impact and uncertainty of reservoir operation for malaria control as the climate changes in Ethiopia]Evaluating the impact and uncertainty of reservoir operation for malaria control as the climate changes in Ethiopia

Cell-phone ready educational videos, translated into local languages, are a recent phenomenon in developing nations. One of the reasons for the emergence of this approach is due to the scarcity of other forms of educational materials with appropriate content for low literate learners. Additionall...


Bello-Bravo, JuliaDannon, E.A.Agunbiade, T.A.Tamo, M.Pittendrigh, Barry R.[The prospect of animated videos in agriculture and health: a case study in Benin]The prospect of animated videos in agriculture and health: a case study in Benin

Plasmodium belongs to the phylum Apicomplexa. Within the Apicomplexa, Plasmodium, Toxoplasma and Cryptosporidium are parasites of considerable medical importance while Theileria and Eimeria are animal pathogens. P. falciparum is particularly important as it causes malaria, resulting in more than ...


Githui, E.G.Villiers, Etienne P. deMcArthur, A.G.[Plasmodium possesses dynein light chain classes that are unique and conserved across species]Plasmodium possesses dynein light chain classes that are unique and conserved across species

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