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A cross-sectional study of serum antibody responses of cattle to tick-borne disease (TBD) parasites (Theileria parva, Theileria mutans, Anaplasma marginale and Babesia bigemina) was conducted on traditional smallholder mixed farms in Mbeere District in Kenya. The objective was to estimate the inf...


Gachohi, John M.Ngumi, P.N.Kitala, P.M.Skilton, Robert A.[Estimating seroprevalence and variation to four tick-borne infections and determination of associated risk factors in cattle under traditional mixed farming system in Mbeere District, Kenya]Estimating seroprevalence and variation to four tick-borne infections and determination of associated risk factors in cattle under traditional mixed farming system in Mbeere District, Kenya

East Coast fever, caused by the tick-borne intracellular apicomplexan parasite Theileria parva, is a highly fatal lymphoproliferative disease of cattle. The pathogenic schizont-induced lymphocyte transformation is a unique cancer-like condition that is reversible with parasite removal. Schizont-i...


Graham, S.P.Pelle, RogerHonda, Y.Mwangi, D.M.Tonukari, N.J.Yamage, M.Glew, E.J.Villiers, Etienne P. de[Theileria parva candidate vaccine antigens recognized by immune bovine cytotoxic T lymphocytes]Theileria parva candidate vaccine antigens recognized by immune bovine cytotoxic T lymphocytes
Ayalew, Y.Gültas, M.Effa, K.Hanotte, Olivier H.Schmitt, A.O.[Identification of candidate signature genes and key regulators associated with Trypanotolerance in the Sheko Breed]Identification of candidate signature genes and key regulators associated with Trypanotolerance in the Sheko Breed

The molecular typing and the indirect ELISA procedure were used to identify some alleles of favorable effect on the antibody response against the Newcastle disease virus (NDV). The NDV seroprevalence was 100.00% with 10.47% suspect and 89.63% positives. The protective level of ELISA antibody mean...


Hako Touko, B.A.Keambou, T.C.Han, J.M.Bembide, C.Cho, C.Y.Skilton, Robert A.Djikeng, AppolinaireOgugo, M.Manjeli, Y.Tebug Tumassang, T.Zoli, P.A.Osama, S.[The Major Histocompatibility Complex B (MHC-B) and QTL Microsatellite Alleles of Favorable Effect on Antibody Response against the Newcastle Disease]The Major Histocompatibility Complex B (MHC-B) and QTL Microsatellite Alleles of Favorable Effect on Antibody Response against the Newcastle Disease

Reassociation kinetics and flow cytometry data indicate that ixodid tick genomes are large, relative to most arthropods, containing ≥ 109 base pairs. The molecular basis for this is unknown. We have identified a novel small interspersed element with features of a tRNA-derived SINE, designated Ruk...


Sunter, J.D.Patel, S.P.Skilton, Robert A.Knowles, Donald P.Scoles, Glen A.Nene, VishvanathVilliers, Etienne P. deBishop, Richard P.[A novel SINE family occurs frequently in both genomic DNA and transcribed sequences in ixodid ticks of the arthropod sub-phylum Chelicerata]A novel SINE family occurs frequently in both genomic DNA and transcribed sequences in ixodid ticks of the arthropod sub-phylum Chelicerata

Vaccines based on recombinant Bm86 gut antigen from Boophilus microplus are a useful component of integrated control strategies against B. microplus infestations of cattle. The capacity of such vaccines to control heterologous infestations by two African tick species was investigated. The mean we...


Odongo, D.Kamau, L.Skilton, Robert A.Mwaura, S.Nitsch, C.Musoke, A.J.Taracha, E.A.Daubenberger, C.A.Bishop, Richard P.[Vaccination of cattle with TickGARD induces cross-reactive antibodies binding to conserved linear peptides of Bm86 homologues in Boophilus decoloratus]Vaccination of cattle with TickGARD induces cross-reactive antibodies binding to conserved linear peptides of Bm86 homologues in Boophilus decoloratus
Falzon, Laura C.Traoré, S.Kallo, V.Assamoi, J.-B.Bonfoh, BassirouSchelling, E.[Evaluation of the fluorescence polarization assay as a rapid on-spot test for ruminant brucellosis in Côte d'Ivoire]Evaluation of the fluorescence polarization assay as a rapid on-spot test for ruminant brucellosis in Côte d'Ivoire

Previous studies using monoclonal antibody (mAb) 4C9 specific for a 32 kDa antigen (p32) of Theileria parva demonstrated expression of the antigen on the surface of the sporozoite, making it a potential antigen for sporozoite neutralization. A full-length cDNA encoding the major merozoite/piropla...


Skilton, Robert A.Musoke, A.J.Wells, C.W.Yagi, Y.Nene, VishvanathSpooner, P.R.Gachanja, J.Osaso, J.Bishop, Richard P.Morzaria, S.P.[A 32 kDa surface antigen of Theileria parva: Characterization and immunization studies]A 32 kDa surface antigen of Theileria parva: Characterization and immunization studies
Thangavelu, R.Mostert, D.Gopi, M.Ganga, P.Padmanaban, D.Molina, A.B.Viljoen, A.[First detection of Fusarium oxysporum f. sp. cubense tropical race 4 (TR4) on Cavendish banana in India]First detection of Fusarium oxysporum f. sp. cubense tropical race 4 (TR4) on Cavendish banana in India

A double bounded contingent valuation (CV) model was used to assess the Willingness to Pay (WTP) for vaccination of cattle against RVF in a sample of 276 livestock producers in Murang’a, Laikipia and Kwale Counties. While the level of awareness about the disease was rather low, nearly all respond...


Wanyoike, Francis N.Mtimet, NadhemBett, Bernard K.[Willingness to pay for a Rift Valley fever (RVF) vaccine among Kenyan cattle producers]Willingness to pay for a Rift Valley fever (RVF) vaccine among Kenyan cattle producers

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