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Salmonella enterica Serovar Typhimurium (S. Typhimurium) is an intracellular bacterium that overcomes host immune system barriers for successful infection. The bacterium colonizes the proximal small intestine, penetrates the epithelial layer, and is engulfed by macrophages and neutrophils. Intrac...


Pardo-Esté, C.Hidalgo, A.A.Aguirre, C.Inostroza, A.Briones, A.C.Cabezas, C.E.Castro-Severyn, J.Fuentes, J.A.Opazo, C.M.Riedel, C.A.Otero, C.Pacheco, R.Valvano, M.A.Saavedra, C.P.[The ArcAB two-component regulatory system promotes resistance to reactive oxygen species and systemic infection by Salmonella Typhimurium]The ArcAB two-component regulatory system promotes resistance to reactive oxygen species and systemic infection by Salmonella Typhimurium

Clostridium difficile is a Gram-positive spore-former bacterium and the leading cause of nosocomial antibiotic-associated diarrhea that can culminate in fatal colitis. During the infection, C. difficile produces metabolically dormant spores, which persist in the host and can cause recurrence of t...


Calderón-Romero, P.Castro-Córdova, P.Reyes-Ramírez, R.Milano-Céspedes, M.Guerrero-Araya, E.Pizarro-Guajardo, M.Olguín-Araneda, V.Gil, F.Paredes-Sabja, D.[Clostridium difficile exosporium cysteine-rich proteins are essential for the morphogenesis of the exosporium layer, spore resistance, and affect C. difficile pathogenesis]Clostridium difficile exosporium cysteine-rich proteins are essential for the morphogenesis of the exosporium layer, spore resistance, and affect C. difficile pathogenesis

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