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Background: Frailty is a geriatric syndrome characterized by a progressive impairment in the subjects’ ability to respond to environmental stress. Frailty is more commonly found in heart failure (HF) patients than in general population and it is an independent predictor of rehospitalization, emer...


Díaz-Toro, F.Nazzal Nazal, C.Verdejo, H.Rossel, V.Castro, P.Larrea, R.Concepción, R.Sepúlveda, L.[Frailty in patients admitted to hospital with acute decompensated heart failure][Factores asociados a fragilidad en pacientes hospitalizados con insuficiencia cardíaca descompensada]Factores asociados a fragilidad en pacientes hospitalizados con insuficiencia cardíaca descompensada

Pérez, OsvaldoCastro Agüero, PabloDíaz Araya, GuillermoNettle Nettle, Daniels MauriceMoraga, FranciscoChiong Lay, MarioJalil Milad, JorgeZalaquett Sepúlveda, RicardoMorán, SergioBecker, PedroCorbalán, RamónLavandero González, Sergio[Persistence of oxidative stress after heart transplantation: A comparative study of patients with heart transplant versus chronic stable heart failure. Persistencia del estrés oxidativo postrasplante cardíaco: estudio comparativo entre pacientes con trasplante cardíaco y con insuficiencia cardíaca crónica estable.]

Castro Agüero, PabloPérez, OsvaldoGreig, DouglasDíaz Araya, GuillermoMoraga, FranciscoChiong Lay, MarioTroncoso Cotal, RodrigoPadilla, IvonneVukasovic Ramírez, José LuisCorbalán, RamónLavandero González, Sergio[Effects of carvedilol on functional capacity, left ventricular function, catecholamines and oxidative stress in patients with chronic heart failure. Efectos del carvedilol en la capacidad funcional, función ventricular izquierda, catecolaminas y estrés oxidativo en pacientes con insuficiencia cardíaca crónica.]

Background: Gender may influence the incidence, severity and hospital mortality due to heart failure (HF). Aim: To evaluate the influence of sex on the proportion of patients hospitalized due to heart failure, its incidence and hospital mortality. Methods: Analysis of the hospital discharge ...


Díaz-Toro, F.Carolina, N.N.Hugo, V.P.[Incidence and hospital mortality due to heart failure. Are there any differences by sex?][Incidencia y letalidad intrahospitalaria por insuficiencia cardíaca en Chile: ¿Existen diferencias por sexo?]Incidencia y letalidad intrahospitalaria por insuficiencia cardíaca en Chile: ¿Existen diferencias por sexo?

Dilated cardiomyopathy is the main cause of heart failure leading to heart transplant.It sprognosisis variable and depends on the etiology, the patient’s ageatonset,and the severity. The management of dilated cardiomyopathy is aimed at minimizing symptoms and preventing disease progression; it re...


Caviedes B., P.Cordova F., T.Larrain V., M.Cruces R., P.[Miocardiopatía dilatada e insuficiencia cardíaca grave. Puesta al día para el médico pediatra][Dilated cardiomyopathy and severe heart failure. An update for pediatricians]Dilated cardiomyopathy and severe heart failure. An update for pediatricians

Objective: The objective of this study was to determine the molecular mechanisms by which cardiac Rho-associated coiled-coil containing protein kinase (ROCK) activation after myocardial infarction (MI) does intervene in cardiac systolic function decline and remodeling. Methods: Simultaneous meas...


Mera, C.Godoy, I.Ramírez, R.Moya, J.Ocaranza, M. P.Jalil, J. E.[Mechanisms of favorable effects of Rho kinase inhibition on myocardial remodeling and systolic function after experimental myocardial infarction in the rat]Mechanisms of favorable effects of Rho kinase inhibition on myocardial remodeling and systolic function after experimental myocardial infarction in the rat

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